I think sometimes one can hit a point, usually during or after massive edits, where it is possible for one to LOATHE their own book.
It is currently happening to me. I am SO SICK of my EMMA story right now. I've finished my third-to-first person edits. I've added 6K words. I've cut about 3K. I've reworked the first five pages about 7959375 times. Because, you know, agents rarely read past the first five pages. Heck, I've heard, recently, that most agents don't read past the first two pages. Unless you hook them, reel them in, and make them happy they continued reading.
Yeah, that's a lot of pressure. The first two pages have to be perfect. Well, the first TEN, because that's usually what they ask for in a query.
I hate my story. I want to never look at it again, for like, months, but since NaNo is coming up, if I don't get it out there before December, it will sit in the growing slush piles with all the NaNo projects. And then the Holidays will happen. And then the New Year, and then, nothing will happen in the month of January, and it will be February before things start rolling again.
Unless I have a KILLER first two pages. Which I'm currently SICK of.
Pphhhhhbbbhhhttttt.